Harm Reduction

Our behavior seems to be built by evolution, and it's sometimes paradoxical. To borrow from the hard sciences, our behavior exhibits complementarity. We are largely felicitous to our family and friends, yet stand-offish (if not aggressive) to “others” we may encounter. Willful ignorance straddles that complementarity borderline. A new study offers insight into what's really going on.
Much of the blood drawn for laboratory analysis is wasted. In a clinical setting where your blood is being taken multiple times a day, wouldn't it be better for the laboratory to use a smaller amount – and let you keep the difference?
Child abuse manifests in various forms. One is the “Shaken Baby,” where rapid head shaking allegedly causes neurological injury and death. Until recently, a constellation of bodily injuries was considered adequate evidence to convict an indicted abuser. No longer. Recent cases have held that “Shaken Baby Syndrome” is not a valid diagnosis. One court just held the diagnosis should be a legal determination – not a medical one, rejecting all medical testimony and exonerating alleged abusers.
To handshake or not to handshake, that is the question. As COVID-19 has moved from a pandemic to an endemic disease, should we greet each other with a shake of hands, fist bump, or just eye contact and walk quickly away?  Handshaking has devolved into a cultural debate rather than the scientific issue of disease transmission. Is handshaking, a form of surface transmission, something to fear?
"[A] censorious report on National Public Radio, citing a poll, accuses Republican voters of being content to 'do nothing' about climate change. In fact, neither party proposes to do anything about climate change. Democrats propose to spend a lot more money doing nothing.” – Holman Jenkins, Wall Street Journal
Are you aware of the concept of the three gates? Most simply, before you speak or – in my case, write – let your words pass through three gates. Is it true? Is it kind? Is it necessary?
In the past week, two Senators questioned a planned study by the FDA on long-acting opioids. They write, “This study is intended to specifically look at the use of EERWs [enrichment enrollment randomized withdrawal] to approve new opioids.” That is not all they got wrong.
“Oregonians voted in November 2020 to stop incarcerating people for using drugs unapproved by the federal government and instead direct resources to harm reduction programs. The pandemic got in the way. Now, while this project is still in its infancy, a group of Oregonians wants to replace something that hasn’t had a chance to work with something that we KNOW hasn’t and won’t work.”
Much has been written about Diversity, Equity, and Inclusion (DEI). Many who are adamant about diversity, especially in regulatory science, are less enthused over equity. I’ve had a few thoughts about both.
The Cochrane Library recently completed a review of “the comparative benefits, harms and tolerability of different smoking cessation pharmacotherapies and e-cigarettes, when used to help people stop smoking tobacco.” Spoiler alert: as we have shown, e-cigarettes are a significant aid in reducing dependency on smoking tobacco.
A recent study of young, deceased athletes exposed to repeated head trauma revealed that 41% suffered severe Chronic Traumatic Encephalopathy (CTE), leading to their death or severe neuropsychological damage. If serious sports injuries are so prevalent, why aren’t we banning the ball?
Is there anything more annoying than walking into a hotel room and seeing the signs to “Save the Environment” by not having the hotel wash your dirty towels? Why should you feel guilty about wanting clean towels after paying high prices for the privilege of staying at their establishment? This was the very situation that led to an essay in 1986 in which the term greenwashing was used for the first time.