The medication causing all the talk is semaglutide (Oh, you mean Ozempic or Rybelsus, both trade names) that are approved for Type II diabetes because they increase insulin production (the within) and thereby improve glucose metabolism.
weight loss surgery
Bariatric (weight loss) surgery works. A severely obese person (BMI > 40) might lose 50 percent of his or her excess body fat in the first year after such surgery.