EPA standards for cancer

World War II ended with the bombings of Hiroshima and Nagasaki. Those bombings and the late effects of radiation on the development of cancers in those “survivors” spurred scientific inquiry into the mechanisms underlying human carcinogenesis – the development of cancer. Today’s regulatory science of chemical carcinogens is based upon assumptions and beliefs that are now 75 years old. Our understanding of carcinogenesis has evolved; should our regulatory models shift?