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The Forced Swim Test, developed in 1977, models depression using mice or rats to screen for antidepressant medications. It has been known for several decades that this test does not replicate depression, resulting in false negatives and false positives, and is no longer used by most pharmaceutical companies. So why does the National Institutes of Health (NIH) continue to fund studies using it? What's it going to take for the NIH to change?

The National Center for Health Statistics reports that overdose deaths have dropped 10 percent over the past year. Is this just a pause in the fatality rate before a climb resumes, or is it the beginning of a new trend? Though it is too early to know the answer, many factors might explain the encouraging new numbers.

As America’s population ages, Medicare will play an even more critical role in ensuring access to high-quality, affordable care for the elderly. Congress must fix the broken Medicare physician payment system.

While ants live forever thanks to a little parasite, humans are too busy popping GLP-1s and obsessively organizing their kitchens to notice. Meanwhile, your happiness may reach a plateau flatter than your bank account after a month of trendy, influencer-driven "fridgescaping."

Recent surprise decisions have upended plaintiffs’ expectations on the toxic tort front. In Delaware, the top court is rehearing the trial court’s evidentiary ruling admitting plaintiffs’ experts’ testimony in the Zantac cases. The Third Circuit has ruled that Monsanto (Bayer) may avail itself of government protection under the pre-emption doctrine, surely launching that issue to the Supreme Court, while individual plaintiffs have scored wins in Roundup exposure cases. And on September 16, an Oregon judge overturned a plaintiff’s verdict for mesothelioma allegedly contracted from using J&J’s talc powder.

This week, Scientific American urged readers to "Vote for Kamala Harris to Support Science, Health and the Environment." It's a senseless, shortsighted move that will inflame America's disdain for science. The upside is that it could incentivize needed reforms in our ideologically slanted academic and public health institutions.

The rapid spread of a new virulent strain of the mpox virus across Africa triggered WHO to declare it a "public health emergency of international concern."

Was Vincent van Gogh the original chaos theorist? While we admire the beauty of “The Starry Night,” physicists decided to crash the party and analyze its swirling sky like a science experiment. It turns out van Gogh wasn’t just painting stars and spirals, he was capturing the essence of turbulent flow. Who needs an advanced degree in fluid dynamics when you have a paintbrush and an eye for chaos?

Much like the Sorcerer's Apprentice, who unleashed a flood by over-relying on enchanted brooms, we seem eager to offload responsibility onto AI while clinging to the illusion of control. In our quest for technological wizardry, research reveals that the presence of a manual mode often leads us to blame people more, even when AI is at fault.

Murder is the unlawful, premeditated killing of one human being by another. It's also considered immoral. Sometimes, however, killing another human can be legal and moral, say during acts of self-defense. But the legal regulation of human killing isn’t uniform, raising the question: if the legal definition of murder can vary, can moral culpability differ as well?

The New York Times recently highlighted how wildfire smoke impacts health, but its coverage missed the mark by not addressing the nuanced science behind particulate matter. As researchers dive into the messy reality of wildfire smoke and its effects, it's clear that relying solely on PM2.5 data doesn't capture the complete picture of health risks.

In a world where we're 99.5% genetically identical, somehow skin color still decides who gets a spot on the kidney transplant list. (Because why fix something when it's clearly broken?) My conversation with Dr. Kevin Pho, discussing "Medicine’s Struggle with Genetic and Social Realities."

Ah yes, the age-old medical mantra: "The solution to pollution is dilution." Apparently, a few squirts of hypertonic saline in your kid’s nose can cut down cold symptoms and keep you from catching their next snot-filled surprise.

Despite a decade of people eyeing their phones like potential death traps, recent studies have put the final nail in the cell-phones-cause-cancer coffin. So, feel free to call, text, or scroll — your brain’s not going anywhere.

Lars Larson began our most recent conversation by noting the increase in life expectancy in the U.S., largely due to advances in drug development. However, he quickly pivoted to criticize current drug shortages, which was the subject of a recent article of mine.

For those aching for a do-over on First Amendment rights and censuring COVID (mis)information on social media, your wish has been granted. Last month, the Ninth Circuit ruled on Facebook’s alleged censoring of anti-vaxx postings by RFK Jr.’s Children’s Health Defense.

While Congress twiddles its thumbs, pharmaceutical giants like Lilly, Pfizer, and Nova Nordisk are revolutionizing healthcare by slashing prices and tossing medical responsibility around like a hot potato. With their new direct-to-consumer model, they’re not just cutting out the middleman but slicing through the fabric of the physician-patient relationship. Who needs accountability when you’ve got savings and convenience?

This week’s reading is a mix of innovation, brainy body connections, and a dash of debunking. Apple engineers are turning AirPods into hearing aids—why stop at music when you can reinvent healthcare? Meanwhile, the vagus nerve is doing its mysterious thing, linking brain and body. And it turns out, that in the Blue Zones, living forever might just be creative bookkeeping.

Calley Means, co-founder of TruMed, recently raised concerns about conflicts of interest within the FDA and the influence of corporate funding on public health guidelines. Thereby, he joined the ranks of Robert F. Kennedy, Jr and his newfound friend, former President Trump, who argued for "a special Presidential Commission of independent minds who are not bought and paid for by Big Pharma."

Ukraine has recently begun deploying drones that drop burning thermite on Russian positions. Thermite, a 130-year-old invention, has proven to be a highly destructive weapon rooted in simple chemistry. However, while the science behind thermite is straightforward, its devastating consequences are far from it.

Ever wonder what it's like to participate in a medical study? When I signed up for a research study, I thought I’d learn something new about diet and health. It turns out that the real learning came from navigating blood tests, stool samples, and questionable food diaries — all while pretending that this was somehow a fun way to spend my time. At least I got a front-row seat to the unglamorous world of clinical research, where the hurdles are real, and the “patients” get a crash course in patience.

Some patients taking weight-loss drugs, like Ozempic, are beginning to report slower or no weight loss as their bodies build up a tolerance to the medication. Does this spell trouble for obese people looking to slim down long-term? Dr. Chuck Dinerstein reports his personal experience with the so-called Ozempic plateau.

Scientists often think they're smarter than they are because of their narrow academic expertise, according to a new study. Recent history is littered with corroborating examples in which experts made false declarations about COVID-19 and refused to acknowledge their errors. What drives this hubris, and how should the public respond to it?

Health is a complex equation with multiple variables: genetics, socioeconomic status, birthplace, luck, and more. The presence or absence of disease is not the only consideration for leading a healthy life. This has shifted how people seek medical care and guidance.

A long-time family friend had to decide whether to undergo five years of antiestrogen therapy following surgery and radiation for her breast cancer. The odds were high that she would be OK without the treatment and only slightly higher with it. Seven years ago, Elle Macpherson had to make the same decision. The right answer? There really isn't one.