There's a vital need for new and effective pain medications. Vertex just announced results from a Phase III study of its experimental drug VX-548. How well does the drug work? It's hard to tell. Here's why.
Drugs & Pharmaceuticals
“The Controlled Substances Act (CSA) places all substances that were in some manner regulated under existing federal law into one of five schedules. This placement is based on the substance’s medical use, potential for abuse, and safety or dependence liability.” The FDA has proposed changing the classification of marijuana from a Schedule I to a Schedule III drug. Let’s break down its thinking.
A new company, Haleon, now sells dozens of products from what was formerly GSK's huge consumer health division, which was spun off in 2022. The company pretends to be highly ethical in its website propaganda, even doing its part to combat climate change by using low-carbon web pages (??). But does it practice what it preaches? Welcome to Voltarengate.
In this radio discussion, Lars Larson and I discuss the efficacy of over-the-counter cold and allergy medications, specifically those containing phenylephrine. The radio host expresses his concern as someone who relies on his voice for his profession, and who occasionally uses these medications to alleviate congestion.
It's just another day when the ingredients on the label of a dietary supplement don't match the contents. But now, given the gummie craze children are more and more likely to mistake melatonin gummies for candy. A study by Harvard's Dr. Pieter Cohen examined the actual vs. claimed doses of melatonin found in 25 online products. The results are horrifying – but not surprising.
A small, but well-conducted, study of the effect of CBD oil on bad toothaches neither proves nor disproves whether the drug works. However, some intriguing data could be confirmed in a larger clinical trial. Let's call this mildly encouraging. At best.
The flawed concept of banning drugs inevitably leads to the appearance of new and worse drugs. Now a class of synthetic opioids called nitazenes, some of which are far more potent than fentanyl, are making their way into the supply of street drugs.
Since 2020, we have been able to buy Advil Dual Action, OTC pills that contain a fixed dose of acetaminophen (Tylenol) and ibuprofen (Advil). Who benefits from combining two medicines into one pill? Is it patients – or GSK that makes the product? I maintain it's the latter.
The DEA recently added six "new" synthetic cannabinoids to its Schedule I list of illegal drugs (aka Spice, K2, bath salts). Has doing this ever worked in the past? No. Will it work now? Of course not. There are plenty of reasons. Here are some of them. Plus, here's another Dreaded Chemistry Lesson from Hell for all you masochists.
A vacation is a tough time to get sick or hurt. It's even tougher when you might have a perfectly legitimate need for a controlled substance, but can't get it from any urgent care facility. The result? Instead of getting an effective drug for what ails you you get tossed out with something nearly worthless. This just happened to my wife. Here's the story. It's infuriating.
A recent survey of pharmacists found that 75% did not have “enough time and personnel to safely perform or meet duties.” This is due, in part, to pharmacists shouldering the extra burden of providing vaccinations. And because 94% of pharmacists work for large corporations, where productivity is measured in prescriptions completed hourly. The typical solution is to increase the number of pharmacists or to turn much of the pharmacy function over to pharmacist-extenders pharmacist technicians. However, there is a simpler solution.
Anyone want to be smarter? Clearly, there's a need; otherwise, I wouldn't have written an article called "Drowning in Morons" in 2020. Perhaps there's a solution. A company is selling a dietary supplement called Smart Drops, which don't just make you smarter but also increase your libido, treat your arthritis, and improve your athletic performance. Believable? Not so much. And let's not forget a Bigfoot spotting - in an MRI facility.