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The Food and Drug Administration recently published an analysis of antibiotic development looking back over the last 40 years. In addition, the paper was accompanied by a compelling editorial. These papers are well worth reading and are highly recommended for everyone, whether they're familiar with antibiotic development or not. And most notably, the hubris of the FDA analysis is astounding.

How old is your dog, in dog years? The widely used rule of thumb – human years x 7 – is apparently incorrect. The science behind the new formula tells us something about extrapolation and a lot about how both we, and our canine friends, age. And the Hanks-dog graph is kinda cool, too.

Telemedicine, what our stories tell us about ourselves, can worms reason, and the role of plate tectonics in our lives and culture.

Do people acquire long-term immunity to coronavirus? Will there be a second wave? Will there be more lockdowns? Some recent news helps shed light on these questions.

The FDA’s rigorous oversight – rather than a race to satisfy an aggressive agenda – is imperative during this pandemic.

Somehow a drug has turned into a political tool. This is nuts. Hydroxychloroquine may or may not end up having any utility as a COVID-fighting drug. But its cardiac toxicity is real, unlike the nonsense surrounding it. Let's stick to the science: Torsades de pointes, not talking points.

Stop me if you heard this one: Fourteen dermatologists walk into a bar... (Actually, it was 8, and 6 other scientists, walked into a February meeting in Germany.) At least 13 (maybe 14) walked out with a coronavirus infection. How did they manage this? Plus a hilarious Oliver North quote, a woefully amateurish food review, and some awful puns. Feel free to add your own.

Should Facebook be in the business of "debunking" news and scientific data when events are rapidly changing? What's true today may be declared false tomorrow, only to be declared true again a week later. Furthermore, does Facebook have the expertise to do so?

A walk on the thoughtful “wild side” of why old-school epidemiology has over-promised and under-delivered, discovering that population density is more than how tightly we are packed, an alternative hypothesis for how sleep refreshes our bodies and spirits, and an update on a maligned energy source, fusion.  

People are hungry for information about the coronavirus. But are some media outlets exploiting the situation to promote themselves?

Open carry means that you may legally carry a loaded weapon visibly on your person. The top photo is over fifty years old, depicting the "Black Panthers"; the bottom picture from last week depicting citizens protesting continued stay-in-place orders.

Everyone knows that the elderly and those with co-morbidities are at greater risk for hospitalization and death from COVID-19. But are all co-morbidities the same? Do some conditions result in more or perhaps fewer hospitalizations and deaths? Let's take a look.

The University of Oxford, in collaboration with British pharmaceutical firm AstraZeneca, has produced a leading coronavirus vaccine candidate. However, the Phase 3 clinical trial was paused because one patient is thought to have developed a serious adverse reaction. What could it be?

The beginner's mind, a video of Tesla production (can you see what is missing?), a video that will put a smile on your face and bring back the joy of opening a present when you were a tween, how will the rise in remote work change our lives, and finally, a question of expertise.

It is difficult to overstate the potential damage that an ineffective or unsafe coronavirus vaccine could inflict on confidence in public health institutions. Conspiracy theories already abound and would multiply further.

Large pharmaceutical companies are multinational organizations with incentives to distribute their vaccines broadly.

In addition to the multiple rhythms that underlie our individual lives, when we come together we tend to "synch" with one another. Whether it be as simple as adjusting the pace of our walking; the give-and-take of our conversation; or as seemingly sophisticated as the murmuration of starlings, it is a biologic phenomenon. How do we entrain, tie together, our independent rhythms?

There are any number of papers supporting the idea that higher levels of air pollution are inversely correlated with poorer health outcomes. These studies all suffer from the fellow travelers of air pollution, traffic density, poverty, and lesser education which confound a clear linkage between air pollution and health. A new study offers a possibility.

The risk to students of reopening schools is quite small. For instance, more young adults aged 15-24 will drown than die from coronavirus. The challenge for re-opening schools is the risk posed to teachers, staff, and students' families.

Did you honestly believe that the CDC announcement six months ago – of a 4.1% decline in drug overdoses in 2018 – was a sign of progress in the so-called war on drugs? Of course, it was nothing of the sort. Just an exercise in tweaking numbers. ACSH advisor Dr. Jeff Singer tells us the real story.

The foundation of medical research, which is considered the gold standard, is the Randomized Controlled Trial when individuals are matched with others, and then randomized to one treatment or another. While the beauty of an RCT lies in its process of deliberate randomness, very little attention has been paid to the integrity of its building blocks: categories. It's time to take a more in-depth look.

"Twelve Diseases That Changed Our World" was originally published in 2007 but has taken on renewed relevance during the COVID-19 pandemic. Will the coronavirus similarly change our world? We review the book authored by Prof. Irwin Sherman.

COVID-19 makes us reconsider so many of our normal activities. Sure, from the perspective of exposure, driving is the safest form of travel. Planes? Perhaps not as much, as corporations and your wallet determine the seating relative to other passengers. But what about trains? Hop on board and find out.

In March I wrote about Phase IIa results of a novel NSAID-like drug ATB-346 (now called otenaproxesul), which is structurally and functionally similar to naproxen (Aleve). But the non-opioid drug lacks its gastrointestinal side effects, especially ulcers. Now Phase IIb results are in and it still looks good. Will it become the first member of a novel class of pain drugs? We could sure use it. A summary of the company's report to shareholders.

A new paper claiming that the SARS-CoV-2 coronavirus was genetically engineered in a laboratory has several red flags. It should not be taken seriously.