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Biopharmaceutical companies, insurers, pharmacy benefit managers and the government can and must work together to keep each other accountable and embrace value-based or outcomes-based reimbursement. The guiding principle being that “IF” the new innovative medicine delivers the outcomes and value promised to patients and the U.S. economy, the therapy will be rewarded.

If we want people to refuse COVID vaccines, a recent CNN segment featuring political pundit Max Boot illustrates how we can do it.

EPIC is arguably THE electronic health record system in the US with the most significant market share (56% of all patient records). Countless millions of federal money have passed into their corporate coffers during our transition to digital record keeping. Artificial intelligence, which is more sizzle than steak, at least medical care has been held out as a grail where the data held in electronic health records could be fashioned to improve medical care. A study from JAMA updates us on that particular marriage.

I've been following (and writing about) Antibe Therapeutics' otenaproxesul, an atypical NSAID without the GI toxicity of Aleve or Advil, since early 2020. It's been nothing but good news. Until now. Otenaproxesul caused a substantial jump in liver enzymes in some clinical trial participants. Can the company overcome this? Wall Street sure doesn't think so.

Is there *nothing* so offensive and juvenile that it's off-limits, even to me? Maybe not.

COVID-19 has brought into sharp relief how little we know about the transmission of respiratory viruses. The pandemic has afforded a great opportunity to improved our knowledge and understanding. A new review summarizes the state of our wisdom.

What could be more delightful than a summer peach? The taste and scent are unmatched in the world of fruit. But beware. Chemicals are responsible for both the taste and scent and the Environmental Working Group doesn't like some of them. The salaries of those at the EWG are just peachy, but the chemical acumen of the group is the pits.

The "Broken Window" theory is among the most widely-known ideas in policing. It’s been very controversial to say the least. But what if we don’t understand how to address the broken window? A new study looks at fixing the window, rather than pursuing the one who threw the rock.

There’s no doubt that obesity is a growing global problem. It lies at one end of the spectrum from its less-discussed – but equally malnourished – polar opposite: hunger. Given that some argue that defining obesity as a disease will change the trajectory of the problem for the better, it’s time for a closer examination.  

So far, 11 different variants of COVID-19 have been identified and assigned a Greek letter for identification. Although delta (originally from India) is making all kinds of trouble worldwide, it will eventually be replaced by something worse. All the more reason to get vaccinated now.

Those of us who are non-millennials may remember back to the 1970s, 1980s, and 1990s when the hottest environmental issue was acid rain. In fact, acid rain generated as much controversy and international conflicts as the big environmental issue of today, climate change, with scientists, policymakers, and politicians engaging in heated battles over this issue.  

Vaccine skeptics continue to insist that the COVID shots are dangerous. As always, their favorite sources are the federal Vaccine Adverse Event Reporting System (VAERS) and other similar passive surveillance databases. As cases of supposed vaccine injury are investigated, we come to the reassuring, though admittedly boring, conclusion that COVID-19 jabs pose a low risk to most people.

The evidence is in: genetic engineering promotes sustainable farming, vaccines save lives, and nuclear energy is our best hope of powering society in a changing climate. But the question remains, how do you convince a generally skittish public to embrace the science behind these technologies? Our answer: make a movie.

Where a product can be found in a supermarket has an impact on its sales. Markets get “stocking fees” for products placed at eye level versus the floor and on “end caps” at the end of the aisles, especially near the registers. What happens if you put more nutritional food at those locations? A new study sheds some disappointing light.

I never really got into fishing, although I have many friends and family who love it. While it’s not the reason I don’t fish, I was surprised to find out recently how hazardous it is – according to statistics, fishing accounts for about 80,000 injuries every year in the US alone, [1] and that doesn’t even get into things like drowning, electrocution, and so forth. And when we look at the dangers of commercial fishing, things get even worse. Reading that chapter made me wonder why any sane person would ever pick up a rod and reel and go anywhere near the water. 

Remember when we all had to turn our cellphones off when planes took off and landed? How about turning them off around medical equipment? It turns out that when we look for something radiating out of cellphones that might harm us, we might consider magnetism.

A group at Sloan Kettering is proposing the use of certain types of chemotherapy drugs to treat SARS-CoV-2 infection. One cannot help thinking of the old adage about what everything looks like when you only have a hammer.

Both mRNA vaccines target COVID-19’s spike, involve two doses, at least currently, and have been widely effective. That hasn’t stopped inquiring minds from wondering whether there are some head-to-head differences in the real world.

Given the abundance of readily available, free, effective (albeit imperfect) vaccines for many months, why are we seeing a surge in COVID cases and hospitalizations? Let's examine the three primary factors that dictate the severity of an outbreak of a viral illness.

The Ivermectin battle rages on. The consensus of scientific and public health opinion is not only that the drug doesn’t work but that it could be dangerous in COVID care. The placebo effect, small sample sizes, improper or absent controls are cited as demeaning the value of studies showing positive results. On the other hand, a coterie of activist proponents aggressively champion its use, both prophylactically and as last-resort care. Case-series and individual miracle results are touted as proof-positive of the drug’s effectiveness. 

A recent article in The Washington Post demonstrates that when opioid medications become less available to veterans, suicide rates go up. And not by a little. This only serves to further show the extent of damage done by foolish U.S. drug policies.

Scope of practice, who can do what to whom, is a contentious area. There is fighting between those with large scopes of practice, such as physicians, and those with a lesser range, like advanced nurse practitioners, physician assistants, and specialty nurses, like those working the critical care areas. Who decides one’s scope of practice? 

YouTube announced last week that it's banning a number of high-profile anti-vaccine activists from its platform. The policy shift is meant to stem the spread of misinformation, but it raises some troubling questions. Most important among them: is more censorship worth the cost it imposes on society?

Statins, which are used in treating heart disease, are among the most widely prescribed medications in the U.S. Diabetes is associated with a very high risk of heart disease. So the thinking has been that a pre-emptive statin, before heart symptoms appear, would be beneficial for those patients. But statins accelerate the progression of diabetes. A new study tries to determine their downsides.

A new wave of lawsuits alleges that the weedkiller paraquat causes Parkinson's Disease. The evidence continues to undermine this claim.