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Those who are not researchers may have wondered how human research is regulated, how research subjects are protected, and how we ensure research is done correctly. Those who do human research know only too well: the Institutional Review Board.

A recent study found that marijuana smoke may cause emphysema. The problem? The study was complete garbage. Celebrities and social-media "influencers" are hyping the weight-loss benefits of repurposed diabetes drugs. Should these medicines really be used to slim down? It's complicated.

Climate change may now be the most cogent global environmental issue of the day. Emissions of greenhouse gases, notably CO2, continue apace, despite angst among environmental groups, and various worldwide governmental goals and pledges. Here I estimate the longitudinal relationships of global mean temperature with population, CO2 emissions, ambient CO2, and gross domestic product (GDP) using 50 years of published annual data.

Asthma is a significant disease; among children, the prevalence is between 7 and 11%. The exacerbation of asthma by second-hand tobacco smoke is well documented, but as smoking tobacco has declined, smoking wacky weed has increased. What effect has this second-hand smoke had on “the children?”

As a memorial to his beloved dog, a retired home builder began making and giving away dog ramps. My elderly Bedlington terrier was one of the beneficiaries.

The death penalty is controversial enough on its own, but when you look at some of the dreadful methods used, mostly due to ignorance and incompetence, there is no way that these executions pass the "cruel and unusual punishment" test that the Supreme Court used in its 2008 decision on lethal injections. They are torture, plain and simple.

If this isn't newsworthy then I don't know what is. At the very least I can promise you that the article is even dumber than the title. Enjoy.

A series of class action cases claim that Zantac can cause cancer. It is not Zantac per se, but a degradation-produced, N-nitrosodimethylamine (NDMA), which may cause cancer at high doses. What do we know about NDMA?

"Holiday Heart Syndrome" is caused by cardiac arrythmias after indulging in rich, salt-laden foods and alcohol. Avoid it.

4-ANPP is not a term that most of you know but it's hugely important. It is the chemical that is the precursor to fentanyl. Although 4-ANPP is not an opioid, there is not a single thing anyone would do with it except convert it to fentanyl. And there is plenty of 4-ANPP to be had now the bad guys use synthetic organic chemistry to make it.

Men will often be boys. Nowhere is this more apparent than in the design of public urinals, where through a moment of frivolity or inattention, the stream goes in a pathway resulting in splashes on the wall and clothing. Physicists attempt to help.

Dreary, despondent headlines about pollution and climate change are the norm. But they are not painting an accurate picture. Many countries are making serious efforts to protect the environment. Human ingenuity is the ultimate resource. My latest over at BigThink.

Artificial Intelligence, or AI, including those large language systems (e.g., ChatGPT), is gaining much traction. When “teaching for the test,” one system passed the U.S. Medical License Exam – a three-component test that's required in order to earn an MD degree. Will doctors be among the first white-collar (white-coat?) workers to be replaced by automation?

Three important findings have emerged from recent research on COVID-19. First, long COVID -- the persistence of symptoms after the acute infection -- is common and can cause significant suffering and disability. Second, the ability of the bivalent booster to broaden recipients' immune response and reduce the frequency of hospitalizations and deaths has exceeded expectations. Third, the data argue for an intensive effort to convince more Americans to get the bivalent booster and to wear masks in moderate- and high-risk situations.

Mara Altman wrote in the NYT that people of shorter stature are better for the planet. Mara claims that the natural resources needed to support a shorter person are less than for a taller person, even though the author acknowledges that shorter people live longer (which may negate the benefits of short stature). Since both genetics and environment determine a person’s height, it was not clear whether the author was advocating that: we manipulate the human genome to breed shorter people, we pair couples to include at least one short partner, or we restrict protein intake with a vegan lifestyle to reduce human stature.

The Pew Organization wanted to see who the American public trusted, so they asked a sample of citizens. Having rounded up the usual suspects, there may be no surprises, but as always, our views can be conflicted.

The traditional view of air pollution is that of bad stuff in the air produced by someone else, the ubiquitous “them.” Recent concerns about indoor air quality may have broadened that view to realize that some “others” may be us. A recent article in the journal Nature proclaimed, “Local and national governments must ensure that good indoor air quality is delivered….” posing the question, delivered by whom? Amazon pristine?

There's a new, proven treatment for COVID-19 called pegylated interferon lambda, but FDA won't approve it, even under Emergency Use Authorization. It's inexcusable.

The American Academy of Pediatrics (AAP) has drawn fire for issuing new recommendations designed to reduce childhood obesity. The AAP's critics are deeply confused.

When government, politicians, and law enforcement take control of the practice of medicine this is what we get: Cruelty and incompetence. The next time you're given Tylenol for a broken leg or post-surgical pain you'll understand. Drs. Jeffrey Singer and Josh Bloom in USA Today.

Vinyl chloride is a dangerous chemical, so the recent derailment and fire of a train carrying a large quantity of it is bad news. Long-time ACSH friend Dr. Joe Schwarcz gives us a lesson on the history and toxicity of the chemical.

News coverage of the East Palestine train derailment has ranged from hysteria to hysteria. One would think that one of the most dangerous chemicals in the world is being discharged from the train. Has anyone bothered to actually examine how toxic vinyl chloride is? You may be surprised.

Many herbal dietary supplements are complex, highly variable, impure, and unsafe. They need better oversight.

Last week the Ninth Circuit Court of Appeals gave the EPA a time-out for bad behavior. In this instance, the EPA determined that glyphosate, the “bad boy” in RoundUp, likely poses no “unreasonable risk” to humans or the environment, yet bollixed up a few steps in their procedures underlying regulatory science.  Why do bureaucracies believe they are exempt from the rules, the same rules that they make?

By now, you have probably seen the headlines asserting that some 13% of Americans have a food addiction to “highly-processed foods.” That number is a result of a poll – not an objective study – but this spotlight provides an opportunity to discuss what we know – and don’t know – about food addiction.