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An FDA panel voted unanimously to withdraw the decongestant phenylephrine (PE) because it shows no benefit, something Sudafed PE users probably learned years ago. But the real story is why phenylephrine was on pharmacy shelves at all. It's all about the DEA and stupid drug policies, a story we've heard many times before.

As an inveterate number cruncher, I couldn’t resist playing with a set of state-level data on prison populations that came my way. It has often been noted that the U.S. has among the highest rates of incarceration in the world. However, most of us feel that we enjoy a basically fair, just, and healthy society even though we are far from leading the world regarding life expectancies.

Everyone should have a primary care provider (PCP), but not everyone does. There are myriad reasons why: some choose not to go to the doctor (hello, young people); some can’t afford care; others may live in provider “deserts” such as rural areas. Whatever the reason, a growing movement exists to expand who can act as a PCP. Chiropractors have been a part of this expansion, but is that wise?

Long COVID comprises a set of persistent symptoms developing weeks after COVID per se has waned. Long COVID cases have been remarkably stable; about 36% of those who had experienced COVID developed long-term symptoms. As such, long COVID deserves more attention.

Did they die from an asteroid or climate?
Fill it up or charge it, please
The untimely and unwarranted death of bees
Woke science

The Guardian's August 17 headline, “Drinking Water of Millions of Americans Contaminated with Forever Chemicals”, was based on newly released data from EPA’s Fifth Unregulated Contaminant Monitoring Rule. Contrary to the headlines blasted in the media, the actual data from this rule shows that Americans have nothing to fear from these chemicals.

The Collyer brothers, Homer and Langley, lived most of their adult lives in a New York City brownstone at the corner of 5th Avenue and 128th Street. Today, their home is a “pocket park,” and the phrase “Collyer Mansion” is firehouse slang for “a dwelling jammed rafter-high with junk.” Together, let’s learn a bit about hoarding.

Whether it's better in the mind’s eye to know one’s biological origins (if born of a donated sperm or egg) – or not – is the subject of much debate. The answer depends on where you were born.

Much of the blood drawn for laboratory analysis is wasted. In a clinical setting where your blood is being taken multiple times a day, wouldn't it be better for the laboratory to use a smaller amount – and let you keep the difference?

Winter is here, which means a barrage of pathogens is patiently waiting to make our lives miserable. Influenza, colds, and the "stomach bug" are the top three nasties likely to get you, but can you prevent this by washing your hands or using an alcohol-based disinfectant? Or maybe neither?

A host of societal problems are associated with social media (SM): Amongst other ills are the dissemination of anti-vax disinformation; being purveyors of anti-Semitic tropes; and fostering narratives resulting in teenage suicide, anxiety, and depression. Until now, host platforms have enjoyed broad protection from legal action –even when dangerous ramifications surface. That may be about to change. 

In a move that will significantly expand the restrictions on per- and poly-fluoroalkyl substances (PFAS) – more commonly known as the “forever chemicals” – the International Agency for Research on Cancer has reclassified perfluorooctanoic acid (PFOA) as “carcinogenic to humans.” It did so even though no valid studies show it increases the risk of causing cancer in people. How will this reclassification increase pressure in Europe and the U.S. for more action? Here's a look.

We know the beat of our heart varies over time, increasing with exertion and slowing with rest or meditation. But, stable as those variations may appear, they vary even within those intervals. Dr. George Lundberg, former long-time editor of JAMA, muses about those variations – termed heart rate variability – and what they might tell us.

Doctors use “diagnostic” labels to describe a condition or constellation of symptoms and signs before determining treatment or rendering a prognosis. Diagnostic criteria generally remain static and serve as a collective reference point for the medical world. Not so for the diagnosis of “excited delirium.”  Not only has the meaning of “excited delirium” morphed over time, but the legal community has conscripted it for non-medical purposes, like defending claims of excessive force by police officers. Recently, the medical community rejected this use and “revoked” the diagnosis. Who benefits?

Once we became aware of our mortality, we wanted to know when death was upon us. While we have forsaken predictions by chicken bones or auguries, today we attempt the same predictive magic. That's at least at the population level, using new chicken bones like our co-morbidities or a frailty index. It should be no surprise that we have enlisted our latest oracle: A.I.

The recent meeting between President Biden and China's President Xi Jinping delved into the U.S. fentanyl crisis, centering on the export of fentanyl chemical precursors from China to Mexico, where they are converted into fentanyl. However, there is an inherent challenge in restricting precursor chemicals. A minimally trained organic chemist can either make them or simply use a different, unrestricted chemical. Thus, any international agreement designed to minimize fentanyl by restricting precursors is likely to fail, defeated by organic chemistry.

Anyone who has spent time in a traffic jam waiting to “get somewhere” can easily accept the premise that traffic can raise your blood pressure. If you don’t believe me, spend 30 minutes going 4 miles in Los Angeles or trying to go over the George Washington Bridge in New York at rush hour. A new study suggests that the creeping elevation of your blood pressure is not so much due to your fellow drivers but to pollutants in the air. Obviously, they haven’t driven in Jersey. What could they be thinking?

In last week’s “Red State/Blue State” square-off between the governors of Florida and California, CA's Gavin Newsom touted his state’s lower per-capita overdose death rate. It might have to do with how the different states compare on harm reduction.

In order to accurately capture the nuance of an article, especially those about scientific and medical matters, headline writers and editors should read the piece before composing a headline.

Curiosity is the insatiable hunger for knowledge and understanding that fuels our exploration of the world. Each of us has curiosity to varying degrees, often for one topic more than another. Curiosity, as with many of our biological drives, has a dynamic quality: waxing and waning. Some researchers were curious.

At the beginning of the year, the CDC and FDA noted “a preliminary safety signal for ischemic stroke among persons aged ≥65 years” who had received the COVID bi-valent vaccine, as well as a similar but "higher" signal in individuals receiving the influenza vaccine at the same time. Now, a study has confirmed that safety signal.

The uptake of the current COVID vaccine is running at about 7% of the U.S. population. Pfizer is taking a significant write-off. After the pandemic, our trust in vaccinations has reached a nadir. It's a far cry from our behavior concerning smallpox in 1947 when, over eight days, over 4 million New Yorkers were vaccinated. Or compared to 1961, when 90% of the at-risk population got vaccinated against polio.

The "wellness" industry has birthed yet another scam: health coaching. Usually lacking any medical or scientific training, these coaches will charge you a king's ransom for useless – and arguably harmful – advice. Buyer beware. Meanwhile, the CDC says everyone six months and older needs COVID boosters. Here's what the data show.

Exa-cel, a new CRISPR-based treatment, modifies the genes of the patient's stem cells to induce them to produce fetal hemoglobin.

A retired psychologist attacked an article of mine about deranged Florida Surgeon General Joseph Ladapo's views of public health policies toward the COVID-19 pandemic. His assertions ranged from the preposterous to the merely inaccurate.