Microbiomes are the collective and highly personal assortment of microorganisms that live in, on, and around us. If genetically modified effectively, these "black boxes" may help us cure cancer, understand how we can adapt to rising temperatures, play a role in mental health, and improve nutrition in children.
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Blowing out candles on a birthday cake. Blah! You'd think this wretched ritual would have disappeared long ago, especially once Covid made its appearance. But people are still doing it. Furthermore, the science to determine whether this practice can make you sick is faulty. Have a strong stomach.
A recent article in USA Today proclaimed that we are *this* far away from no longer having working antibiotics, a cataclysmic development that would pose "an existential threat for modern medicine." Is this really true? Let's ask Dr. David Shlaes, one of the foremost experts in the world of antimicrobial science.
β‐Hydroxy‐β‐methylbutyrate, aka, HMB, is a very safe supplement used to build muscle. But a group has recently demonstrated that HMB may also have properties to mitigate the symptoms of Alzheimer's in mouse models of AD. Could this be a useful drug in protecting the brains from the ravages of this awful disease?
The International Agency for Research on Cancer's (IARC) conclusion that the sweetener aspartame "possibly" causes cancer is ... definitely stupid. Meanwhile, you can eat a diet consisting of 91 percent "ultra-processed" food and be healthy. So says a new study. Let's take a closer look.
Peer-reviewed research is the gold standard for science. We rely on that system to weed out the discoveries from the detritus. However, growing concerns over how the peer-review system operates are forcing the academic community to take a long, hard look at the process and ask, “How can we improve this?”
Are impending drug DUI laws scientifically justified, accurate, or fair? If you're pulled over for a traffic violation in certain locations and asked to take a roadside saliva test, you may learn they're anything but. Drs. Josh Bloom and Henry Miller discuss this in an opinion piece published in the law journal Law360.
You may want to procure an air sickness bag before you read this. What's worse: A cigarette company portraying smoking as sexy (and it's not the least bit subtle) or a 1970 ad proudly proclaiming, "You've come a long way, baby" (as if the women's rights movement somehow empowered women by giving them their own brand of cigarettes)?
Could the news on the environment get any worse? Every day, we are inundated by stories about extreme weather events, including floods, hurricanes, extreme heat, a global water crisis due to severe droughts, and a food crisis resulting from declining land suitable for agriculture. But there is some good news to report. Innovation is driving solutions to many of these problems. Perhaps the situation is not as dire as the news reports.
Now that prospective parents have the option to genetically design their kids (at least to a point), what does this mean to society in terms of other responsibilities involved in child-making?
The media reports that colchicine, a very old drug, has now been discovered to reduce the risk of recurrent heart disease and has a new FDA indication. Of course, the “discovery” has taken 10 years, and the data for the FDA approval is from 2020. Just how helpful will colchicine be to you and me?
A new study suggests that the antiviral Molnupiravir may “paradoxically” be driving COVID-19 mutations, creating variants of concern. What is going on? It is all about molnupiravir’s mode of action and evolution.
A new study of associations between incident dementia and air pollution caught my attention because air pollution studies like this have been driving me toward dementia for decades. Let’s unpack their findings.
There’s something about autism that invites scapegoating. The latest attack was on makers of Lexapro, the anti-depressant medication, when used during pregnancy. Six plaintiffs recruited three experts to testify to a supposed causal connection between the drug and their children’s affliction. The court rejected the expert testimony outright and dismissed the case. Three weeks ago, the Second Circuit affirmed. The decisions, while applaudable, are problematic.
In case you haven’t noticed, the coronavirus is still with us. The First Lady has COVID-19, and cases and hospitalizations are rising. Some people where I live are wearing masks, and one of them has Long Covid. The virus is likely in our sanitary sewer systems, and we are responsible for putting it there.
If you’ve been following the news, you’ll have noticed that Japan started discharging its tritiated water into the ocean last week, over the objections of China and South Korea and with the concurrence of the International Atomic Energy Agency. I noticed there were a few comments on my recent ACSH piece on this matter and thought I’d address a few of the points raised in the comments.
“Last month, California lawmakers passed a bill that would decriminalize the personal possession of small amounts of a few plant-based psychedelics. This raised hopes that this could be the first of many reforms to unlock the therapeutic potential of psychedelics. Unfortunately, Governor Newsom vetoed the bill, citing reasons that can only be characterized as specious.”
Some people drink coffee, and the next thing you know, they're trying to climb the Empire State Building. But others feel little or nothing. What's going on?
Advil, aka, ibuprofen, is one of the most widely used drugs in the world. It's effective for relief of pain, inflammation, and fever. It can also wreak holy hell on your stomach. Unfortunately, the two effects go together. Grab the Rolaids. It's time for an Advil lesson.
Flu shots perform inconsistently because it's hard to anticipate which strains of the virus will be circulating in a given year. So far in 2023, it appears that the latest round of vaccines are working well. The FDA has determined that Sudafed PE doesn't work. Questions and accusations are flying as a result: why were we sold a useless decongestant in the first place? And more importantly, who's to blame for this public health blunder?
An email from Dr. Kan Shao, a professor at Indiana University School of Public Health, states that EPA’s current version of Benchmark Dose Software modeling is “extremely misleading and not scientifically justified.” It is very unusual for a scientist who has been deeply involved with the EPA in developing risk assessment modeling to openly criticize the EPA. This requires a deeper dive into this issue.
Sickle Cell Disease is an awful genetic disease that disproportionally affects black people. It's caused by a single-point mutation in DNA, which results in a modified hemoglobin protein, differing by only one amino acid. While this may sound insignificant, it's anything but. Simple organic chemistry explains why this change profoundly affects those unfortunate enough to inherit the disease, which is characterized by abnormal hemoglobin.
A recent study from JAMA Internal Medicine documents that in many cases in which a patient has died, the electronic medical record – the baseline truth for Big Healthcare Data – lists them as alive. Does the term "garbage in, garbage out" ring some bells?
What is our most important organ? Every time there was a new lecturer in medical school, they began by pointing out why their organ of interest was the most important. After all:
Those buildings we call supermarkets are laid out to encourage us to buy. It is not a coincidence that magazines and candy are displayed at the register, nor the fact that the food you really want is in the back, so you have to transverse the whole store to find it. Are our online purchases, without that physical organization, the same? Short answer: no.
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